On a 2x2x4, if solving center layers then outer, what is the probability of an outer layer skip (both of them)?
There are 8 corner pieces remaining after the two inner layers have been solved, and all 8! permutations of those pieces are possible. There is no concept of corner orientation, so you can ignore this. Lastly, count how many "solved" states there are, allowing for the possibility of an AUF on either the U or D layers alone, or on both layers. Set this up as a fraction to calculate the total probability.
In case you haven't noticed, I'm purposefully not actually answering your question. The reason for this is that knowing how to calculate probabilities like this one is a good stepping stone for how to calculate the more complex ones. If my hints don't help, reply in this thread or PM me, but try to start from there and see if that helps.
Chris