I believe analysis of movecounts in ZZF2L vs CFOP F2L show that they have comparable qtm, so I am not sure the efficiency gains given by ZZF2L are as much as you say. (QTM here because I think in this situation it's the best measure of how fast the F2L can be. I will also take insertions like R U' R' over R U R any day).
From what I've seen of CFOP reconstrutions, it's got rotations (aka regrips i guess but i mentioned rotations), then regripless tps spam per pair. Maybe 1 rotation in the middle of a pair, but again, that's rotations. Sure, CFOP sometimes switches between L and R but never in the way that ZZ will. L2/R2 as well still can't really be ignored; these are what make htm efficiency less relevant here, basically forcing regrips and disrupting flow