The whole premise is good, but the idea of a best 3x3 method is a far reaching one, as there will always be a consequence of which one criteria that the current speedcubing methods has is checked while others don’t (ergonomics, rotationless, TPS, algorithmic)
I believe with the state of cubing now, just about all of possible best candidates has been exhausted, so maybe instead of thinking of creating a new best method, we should create a method that answer one or two problem.
I happen to hate doing the F & B move more than any other, and so I incorporated a variant of the Lau method that has no F & B and no rotations in every step but of course at the cost of higher move count. How about others? What are perhaps certain things you find awkward or want to eliminate in solving, then maybe try to find a solution to never have that in your solves.