In F2L I use URU'R' because it is better for lookahead for me and I regrip to do R'FRF'. I often do cube rotation to avoid R'FRF'. However there are exceptions, like there is a shortcut R'F2RF2 which I use because it is 4 move.
U R U' R', because I change my grip when I do R' F R F'. I grip with my thumb on F, middle finger on B. For R' F R F' I place the thumb on D, middle finger on U so I can do the F' using my left hand's index finger.