Apparently this is controversial but yes, it does.
If you want to learn poker, you don't immediately jump into learning about balancing cbetting frequencies or polarising your range from the SB, nor if you learn chess, do you immediately go into learning about lategame king play.
By learning certain algorithm sets or focusing on f2l tricks at the wrong stage, you'll set yourself behind because it will create a cognitive prioritisation of what you've learned rather than what is best.
I don't think this is determined by a flat value ('don't learn this before sub n!') but more to do with factors like experience or overall efficiency or amount of bad tendencies. For example, I think it's silly to start thinking about pair selection when you're having trouble even looking ahead one pair, or having trouble solving that pair efficiently. Similarly, it's suboptimal to work on learning CPOLL when your OLLs are still at >2.5s for recog+exec, since your overall times will decrease that much through unfamiliarity that the supposed benefits (better PLLs) are totally outweighed.
There is an Expected Value for how much each separate 'thing' to learn or practise will benefit you and this changes over time. For example, the expected value of CPOLLs as a group decrease the faster the rest of your PLLs are in respect to those algorithms + your recognition. If utilising CPOLL has no cost then it is purely better since you increase the chance of skips and EPLLs (which for some are faster than the avg PLL). For myself, as someone who doesn't practise frequently, CPOLL is a detriment since my PLLs are all around the same speed, yet my recog+exec of many CPOLLs is slower than the average pure OLL. I basically don't get benefits from EPLLs and the increase in skip chance is pretty much negligible - it just increases the the variance of my times.
Of course, this is answering all in respect to getting as fast as you can be, as efficiently as possible. From a hobbyist point of view then you can learn whatever the hell you want, whenever, as long as you're enjoying yourself.
I never understood why anyone would use keyhole when there is Oka. I mean they are practically the same thing except that keyhole wastes more moves to insert the last top edge... But then again that's just me
