Possible Yau3 idea I had. No idea if it will work.:
1) Build Roux 1x2x3 block on left.
2) Use <R, U, r, M> to solve FD, BD, & F & B centers intuitively. This can be done usually pretty quickly & resembles Yau centers.
2a) EO maybe?
3) Solve rest of cube with CFOP.